The Use of 2-Octylcyanoacrylate Dressing in Reducing the Risk of Superficial Surgical Site Infections in Colorectal Stoma Surgery: A Retrospective Cohort Study

Background: Superficial surgical site infection (SSI) is a common morbidity following bowel resection surgery involving stoma formation with clinical and financial implications. The study aimed to evaluate the role of topical skin adhesive, 2-octylcyanoacrylate (Dermabond®) (2-OCA) in reducing wound infections colorectal surgery. Methods: We performed retrospective, single-centre, cohort using notes. All patients, over age 18, undergoing either elective or emergency, five years from January 2015 December 2019 were included. primary endpoint was SSI, defined by manifestation inflammation including pain, erythema, discharge, regardless microbiological culture results. Patients received 2-OCA glue as dressing standard firm adhesive e.g. Opsite. Results: Overall, 604 patients included study. median 67; 187 (31%) Dermabond (Group 1) 417 (69%) care 2). A total 288 (47%) female, 134 (22%) had body mass index (BMI) greater than 30, 87 (14%) diabetic, 90 (15%) smokers. 279 (46%) an American Society Anesthesiologists (ASA) score 3 4; 282 went through emergency surgery, (64%) underwent dirty 220 (35%) developed SSI. BMI 30 compared < (OR: 2.32, 95% CI: 1.54-3.49, p<0.0001), diabetes no 0.54, 0.32-0.92, p<0.0241), clean 2.26, 1.51-3.37, p<0.0001) care, use 1.52, 1.03-2.24, p=0.0343) associated SSIs. Conclusion: Our demonstrates that there association between reduced SSIs when methods dressing. Further randomised trials are recommended strengthen this evidence demonstrate causation.